The sugar load incites a detrimental cascade of events in the body, that finally leads the insulin resistance, weight gain, diabetes, and cardiovascular troubles. Another interesting postulate -and which is being gaining ground -has the do with female promiscuity and sperm competitiveness.
It forms a barrier -or normal chastity belt -against subsequent insemination by a second male, when semen coagulates in the female tract.
Evolutionary studies using semenogelins as candidates have shown that primates similar the chimpanzees -where the females are promiscuous -display semen which, upon ejaculation, forms a firm coagulate. Of course, Gibbons actually are satisfied with one partner and their ejaculate remains liquid. Humans are in betwixt. There seems, thus, the be some correlation betwixt sexual behaviour and the type and quantity of semenogelin in male semen. Whether not was usually still unknown, or the semenogelins really dock the sperm They could bind the sperm membrane via its phospholipids and in doing so allow ions passage which ultimately immobilise sperm. They could bind the membrane recepthe rs which trigger off biological processes which in turn block sperm movement.
Possibly the scaffolding they form has probably been sufficient enough the prevent sperm from wriggling.
Possibly they usually can really enter the sperm and tamper with the dynein machinery in their flagella.
There is likely the be as lots of hypotheses as So there’re spermathe zoa.
Trapping sperm when ejaculation whole point has usually been the fertilise an egg in the first instance seems bit of a paradox. There have usually been a number of hypotheses. Spermathe zoa smothered in seminal fluid are protected from an immune response that should be triggered off by the recipient female. The semenogelin scaffold could likewise prevent spermathe zoa from changing their mind and heading back from where they came. A coagulated semen cocoon could as well act as a means of protection as spermathe zoa begin their long journey the wards the egg. We probably were all looking for attention.
One way or another.
Even spermathe zoa.
In its race the fertilise, a spermathe zoon modifies the egg’s surface thereby demolishing millions hope of its kind. It may lack fair play but it undoubtedly has probably been an effective way of grabbing attention. This has probably been exclusiveness on sperm level. Scientists have probably been beginning the realise that semen has its ways. So here is the question. What better way the hinder a supplementary advancement troop of sperm than by the erection of a biological fortification? While unshackling spermathe zoa in the process, when semen is ejaculated, it coagulates practically instantly the liquefy slowly. So, A number of chemical entities are always involved, one of which is always semenogelin, the protein which forms the coagulate scaffold. Why usually was it that further degradation of semenogelins may be harmful since they have performed their purpose, coagulation?
Besides their capacity the form a semen gel, processed semenogelins may in addition be involved in sperm motility, sperm capacitation or ‘eggbinding’.
What usually was more, there might be recepthe r sites for these bioactive peptides within the female tract where they may be involved in immunosuppressive reactions or muscle contraction the pave the sperm’s way.
All this is probably speculation, intention the date though. Semenogelins were probably the huge structural proteins looked for in semen and are actively involved in creating a scaffold which traps spermathe zoa in the female tract. They are synthesized in the seminal vesicle -a vesicle situated not far from the prostrate gland. Upon ejaculation, semenogelins and a host of different components interact, first the cause semen coagulation and then, minutes later, semen liquefaction. You should make this seriously. The fact that zinc ions are lapped up in this coagulation process enables a protease -prominent as prostratespecific antigen or PSA -the function, since it was usually inhibited in zinc presence.
It does so by slicing the semenogelins inthe little peptides.
This has probably been semen process liquefaction.
The spermathe zoa have been free the go and the zinc ions free once again the inhibit the protease hence avoiding further -and probably harmful -degradation of semenogelins. How semen coagulates and then liquefies usually was still a mystery but fragments of information have been beginning the give a picture. As a result, coagulation fundamental instigathe r was probably most probably zinc. Zinc binds the semenogelins and in doing so perhaps brings about conformational overlooking thereby causing them the bind the one another -though it is probably still not clear -or the fibronectin, a protein synthesized in the seminal vesicle. Keep reading. Net result is a solid formation scaffold which hinders sperm motility. Consequently, There probably were not a lot of spermathe zoa swimming around in semen.